M3S3

Microbial Metagenomics Mock Scenario-based Sample Simulation tool

System Features

M3S3 Sample Simulation tool features


On Demand

Capable of producing a variety of virtual metagenomics samples on-demand, simulating a spectrum of clinical diagnostics scenarios of varying complexity.

FASTQ / FASTA input

Allows for the use of real FASTQ format sequence reads and FASTA format assembly sequence data as an input for the virtual samples.

Flexible

User capability to define the abundancy (or ratios) of the sequences composing the virtual sample.

Multi-platform

Supports long read platforms, namely Pacific Biosciences and Oxford Nanopore.

QA

Useful for the development, and integration of robust, standardised and reproducible metagenomics analysis software into the clinical microbiology laboratory’s diagnostics workflow.

User Friendly

User-friendly web interface.

Clinical Scenarios

M3S3 tool has been validated using relevant clinical microbiological scenarios.

Validation

To perform ‘road-testing’ of new metagenomics software and validation of metagenomics pipelines.

Developers

M3S3 Development Team


Bioinformatics:

Dr. Yair Motro Moran-Gilad Lab
Faculty of Health Sciences
Ben-Gurion University

Clinical Microbiology, PI:

Prof. Jacob Moran Gilad, MD MPH Dept. of Health Systems Management
Faculty of Health Sciences
Ben-Gurion University

Web Development:

Mr. Ruslan Sergienko Medical Computing Unit
Faculty of Health Sciences
Ben-Gurion University

Funding:

Ministry of Defense State of Israel